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Literature summary for 3.4.22.1 extracted from
- Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice (2019), Aging Cell, 18, e12856 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P10605 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| microglia | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CatB | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | increase and leakage of CatB in microglia during aging are responsible for the increased generation of mitochondria-derived reactive oxygen species and proinflammatory mediators, culminating in memory impairment | Mus musculus |
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Release 2023.1 (January 2023)
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