Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-(trans-epoxysuccinyl)-L-leucine 4-guanidinobutylamide | addition of E-64 significantly decreases the activities of cathepsin B and caspase 3, and TUNEL-positive cells in heat-shocked in vitro maturated (IVM) bovine cumulus-oocyte complexes. Addition of inhibitor during in vitro maturation under heat shock conditions significantly improves both developmental competence and quality of the produced embryos | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | P07688 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
oocyte | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
heat-shocked in vitro maturation (IVM) of bovine cumulus-oocyte complexes show significantly high activities and expressions of both cathepsin B, and caspase 3 accompanied by a significant increase in number of TUNEL-positive cells | Bos taurus |
Synonyms | Comment | Organism |
---|---|---|
cathepsin B | - |
Bos taurus |
General Information | Comment | Organism |
---|---|---|
physiological function | present results implicate cathepsin B activity as one of the possible pathways that are responsible for heat shock-induced apoptosis in bovine cumulus-oocyte complexes | Bos taurus |