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Literature summary for 3.4.22.1 extracted from

  • De Vries, E.; Bakker, N.; Krijgsveld, J.; Knox, D.P.; Heck, A.J.; Yatsuda, A.P.
    An AC-5 cathepsin B-like protease purified from Haemonchus contortus excretory secretory products shows protective antigen potential for lambs (2009), Vet. Res., 40, 41.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.1

Application

Application Comment Organism
additional information the purified AC-5 is usel for vaccination of lambs against Haemonchus contortus infection Haemonchus contortus

Inhibitors

Inhibitors Comment Organism Structure
cystatin binding sequence is FFEYDGVVSGGPYLGK, by mass spectrometric analysis Haemonchus contortus
E64
-
 Haemonchus contortus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular the enzyme is secereted Haemonchus contortus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
 x * 43000, SDS-PAGE Haemonchus contortus

Organism

Organism UniProt Comment Textmining
Haemonchus contortus O44396
-
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme from sheep feaces by cystatin affinity chromatography or by affinity chromatography on a resin with immobilized recombinant Cooperia punctata Cp-ASP-1a protein, expressed in Escherichia coli Haemonchus contortus

Subunits

Subunits Comment Organism
? x * 43000, SDS-PAGE Haemonchus contortus

Synonyms

Synonyms Comment Organism
AC-5
-
 Haemonchus contortus
cathepsin B-like AC-5
-
 Haemonchus contortus
cathepsin B-like cysteine protease
-
 Haemonchus contortus