Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | required to reduce the enzyme to its catalytically active form | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2] | i.e. (PMRu52), a ruthenium(II) compound acting as a strong inhibitor of cathepsin B, crystal structure and binding structure analysis, overview | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Bos taurus | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Bos taurus | - |
spleen | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-benzyloxycarbonyl-L-lysine 4-nitrophenyl ester + H2O | - |
Bos taurus | N-benzyloxycarbonyl-L-lysine + 4-nitrophenol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cat B | - |
Bos taurus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
assay at | Bos taurus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0055 | - |
pH 6.0, 30°C | Bos taurus | trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2] |