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Literature summary for 3.4.22.1 extracted from

  • Kolwijck, E.; Massuger, L.F.; Thomas, C.M.; Span, P.N.; Krasovec, M.; Kos, J.; Sweep, F.C.
    Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors (2010), J. Cancer Res. Clin. Oncol., 136, 771-778.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
diagnostics cathepsin B is a possible prognostic biomarker for the aggressiveness of ovarian cancer, overview Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
cystatin C
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ovarian cyst fluid of ovarian tumors, the levels of CatB depend on the tumor subtypes, overview. CatB levels are signifiantly higher in cystic fluid of malignant serous tumors compared to those found in benign serous tumors Homo sapiens
-

Synonyms

Synonyms Comment Organism
CatB
-
Homo sapiens

General Information

General Information Comment Organism
additional information increased CatB expression in malignant ovarian tumors might be balanced by a corresponding increase in inhibitor CysC, overview Homo sapiens