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Literature summary for 3.4.22.1 extracted from

  • Zhang, C.; Sun, J.B.; Liu, D.C.; Cui, Y.Q.; Liu, S.; Sun, H.C.
    Preliminary research on the pathological role of cathepsin-B in subcutaneous heteroplastic pancreatic carcinoma in nude mice (2009), Chin. Med. Sci., 122, 2489-2496.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
CA-074-Me CA-074Me clearly inhibits cath-B expression in the subcutaneous heteroplastic pancreatic carcinoma model, and demonstrates an anti-neoplastic and anti-angiogenesis effect, overview Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
female BALB/c nude mice
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreatic cancer cell from subcutaneous heteroplastic pancreatic carcinoma, quantitative cathepsin B expression analysis and modelling Mus musculus
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Synonyms

Synonyms Comment Organism
Cath-B
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Mus musculus
cathepsin-B
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Mus musculus

General Information

General Information Comment Organism
malfunction cathespin-B is an important proteolytic enzyme involved in the disease course of invasion in many types of cancer. It correlates with the growth and angiogenesis of tumors, but not with the adhesion induced by CD44v6, in the subcutaneous heteroplastic pancreatic carcinoma model, overview Mus musculus