Literature summary for 3.4.22.1 extracted from

Hook, V.Y.; Kindy, M.; Reinheckel, T.; Peters, C.; Hook, G.
Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein (2009), Biochem. Biophys. Res. Commun., 386, 284-288.

Search for more literature for 3.4.22.1

Application

Application	Comment	Organism
drug development	cathepsin B is a target for development of inhibitors to lower amyloid-beta protein in Alzheimer's disease	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	generation of cathepsin B deficient mice. Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein. No phenotypes, overview	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	C57BL/6 mice	-
Mus musculus C57BL/6	-	C57BL/6 mice	-

Synonyms

Synonyms	Comment	Organism
CatB	-	Mus musculus

General Information

General Information	Comment	Organism
malfunction	genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein	Mus musculus

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Release 2023.1 (January 2023)