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Literature summary for 3.4.22.1 extracted from

  • Abdulla, M.H.; OBrien, T.; Mackey, Z.B.; Sajid, M.; Grab, D.J.; McKerrow, J.H.
    RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model (2008), PLoS Negl. Trop. Dis., 2, e298.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.1

Protein Variants

Protein Variants Comment Organism
additional information suppression of cathepsin B by doxycyclin-induced RNAi results in parasite clearance from the bloodstream and prevents a lethal infection in mice causing African trypanosomiasis, overview Trypanosoma brucei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Trypanosoma brucei cathepsin B plays a key role in parasite infection, overview ?
-
 ?
additional information Trypanosoma brucei 90-13 cathepsin B plays a key role in parasite infection, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei
-
-
-
Trypanosoma brucei 90-13
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cathepsin B plays a key role in parasite infection, overview Trypanosoma brucei ?
-
 ?
additional information cathepsin B plays a key role in parasite infection, overview Trypanosoma brucei 90-13 ?
-
 ?

Synonyms

Synonyms Comment Organism
CatB
-
 Trypanosoma brucei