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Literature summary for 3.4.22.1 extracted from

  • Herszenyi, L.; Farinati, F.; Cardin, R.; Istvan, G.; Molnar, L.D.; Hritz, I.; De Paoli, M.; Plebani, M.; Tulassay, Z.
    Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer (2008), BMC Cancer, 8, 194.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
additional information cathepsin B is a marker for malignant diseases such as colorectal cancer, diagnostic accuracy, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens cathepsin B, together with cathepsin L, urokinase-type plasminogen activator and its inhibitor PAI-1, plays an important role in colorectal cancer invasion. Correlation analysis of proteolytic enzymes in colorectal cancer, overview ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
adenoma cell tubular adenomas with low grade dysplasia and tubulovillous adenomas with high grade dysplasia Homo sapiens
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colorectal cancer cell
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Homo sapiens
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additional information quantitative determination of cathepsin B tissue distribution Homo sapiens
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ulcerative colitis disease specific cell type
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Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cathepsin B, together with cathepsin L, urokinase-type plasminogen activator and its inhibitor PAI-1, plays an important role in colorectal cancer invasion. Correlation analysis of proteolytic enzymes in colorectal cancer, overview Homo sapiens ?
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?

Synonyms

Synonyms Comment Organism
CatB
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Homo sapiens