Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | activates | Schistosoma mansoni |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-Leu-Leu-Tyr-CHN2 | - |
Schistosoma mansoni | |
benzyloxycarbonyl-Trp-Met-CHN2 | - |
Schistosoma mansoni | |
L-3-carboxy-2,3-trans-epoxypropionyl-leucylamido-(4-guanidino)butane | E-64 | Schistosoma mansoni | |
L-trans-epoxysuccinyl-3,5-diiodo-L-tyrosylamido(3-methyl)-butane | compound 13b | Schistosoma mansoni | |
L-trans-epoxysuccinyl-3,5-diiodo-L-tyrosylamido(3-methyl)-butane ethylester | compound 13a | Schistosoma mansoni | |
N-(L-3-trans-carboxyoxirane-2-carbonyl)-Ile-Pro | CA-030 | Schistosoma mansoni | |
N-(L-3-trans-propylcarbamoyloxirane-2-carbonyl)-Ile-Pro | CA-074 | Schistosoma mansoni | |
peptidyl diazomethyl ketone derivatives | peptidyl diazomethanes | Schistosoma mansoni |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.021 | - |
benzyloxycarbonyl-Phe-Arg-4-methylcoumaryl-7-amide | - |
Schistosoma mansoni | |
0.041 | - |
benzyloxycarbonyl-Arg-Arg-4-methylcoumaryl-7-amide | - |
Schistosoma mansoni |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Proteins + H2O | Schistosoma mansoni | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schistosoma mansoni | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Schistosoma mansoni |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide + H2O | - |
Schistosoma mansoni | benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin | - |
? | |
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin-7-amide | - |
Schistosoma mansoni | benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin | - |
? | |
globin + H2O | - |
Schistosoma mansoni | partially degraded globin | - |
? | |
Proteins + H2O | - |
Schistosoma mansoni | ? | - |
? | |
serum albumin + H2O | - |
Schistosoma mansoni | partially degraded serum albumin | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
12.2 | - |
benzyloxycarbonyl-Arg-Arg-4-methylcoumaryl-7-amide | - |
Schistosoma mansoni | |
49.5 | - |
benzyloxycarbonyl-Phe-Arg-4-methylcoumaryl-7-amide | - |
Schistosoma mansoni |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4 | 5 | globin degradation | Schistosoma mansoni |