Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreatic cancer cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Z-Gly-Pro-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PREP | - |
Homo sapiens |
prolylendopeptidase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | depletion/inhibition of prolylcarboxypeptidase (PRCP)/prolylendopeptidase (PREP) suppresses rapamycin-induced activation of PI3K/AKT with consequent additive/synergistic cytotoxicity | Homo sapiens |
physiological function | PRCP and PREP regulate IRS-1 stability and PI3K/AKT activation in pancreatic cancer | Homo sapiens |