Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(S)-1-((S)-1-(4-phenylbutanoyl)-pyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile | KYP-2047, most potent inhibitor | Homo sapiens | |
(S)-1-((S)-1-(4-phenylbutanoyl)-pyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile | KYP-2047, most potent inhibitor | Rattus norvegicus | |
Boc-Asn-Phe-Pro-aldehyde | - |
Homo sapiens | |
Boc-Asn-Phe-Pro-aldehyde | - |
Rattus norvegicus | |
Z-Pro-Pro-aldehyde-dimethylacetal | - |
Homo sapiens | |
Z-Pro-Pro-aldehyde-dimethylacetal | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
cytosol | - |
Rattus norvegicus | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
x * 80000, SDS-PAGE | Homo sapiens |
80000 | - |
x * 80000, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortical neuron | - |
Rattus norvegicus | - |
SH-SY5Y cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-benzyl 2-(2-(4-hydroxynaphthalen-1-ylcarbamoyl)pyrrolidin-1-yl)-2-oxoethylcarbamate + H2O | specific substrate, UAMC-00682 | Homo sapiens | ? | - |
? | |
(S)-benzyl 2-(2-(4-hydroxynaphthalen-1-ylcarbamoyl)pyrrolidin-1-yl)-2-oxoethylcarbamate + H2O | specific substrate, UAMC-00682 | Rattus norvegicus | ? | - |
? | |
Gly-L-Pro-4-nitroanilide + H2O | - |
Homo sapiens | Gly-L-Pro + 4-nitroaniline | - |
? | |
Gly-L-Pro-4-nitroanilide + H2O | - |
Rattus norvegicus | Gly-L-Pro + 4-nitroaniline | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 80000, SDS-PAGE | Homo sapiens |
? | x * 80000, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
PREP | - |
Homo sapiens |
PREP | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00000029 | - |
cell free assay, pH and temperature not specified in the publication | Rattus norvegicus | (S)-1-((S)-1-(4-phenylbutanoyl)-pyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile | |
0.00001 | - |
in situ assay, pH and temperature not specified in the publication | Homo sapiens | (S)-1-((S)-1-(4-phenylbutanoyl)-pyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile | |
0.000733 | - |
cell free assay, pH and temperature not specified in the publication | Rattus norvegicus | Z-Pro-Pro-aldehyde-dimethylacetal | |
0.00204 | - |
cell free assay, pH and temperature not specified in the publication | Rattus norvegicus | Boc-Asn-Phe-Pro-aldehyde | |
0.00294 | - |
in situ assay, pH and temperature not specified in the publication | Homo sapiens | Boc-Asn-Phe-Pro-aldehyde | |
0.005111 | - |
in situ assay, pH and temperature not specified in the publication | Homo sapiens | Z-Pro-Pro-aldehyde-dimethylacetal |