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Literature summary for 3.4.21.26 extracted from

  • Mitea, C.; Havenaar, R.; Drijfhout, J.W.; Edens, L.; Dekking, L.; Koning, F.
    Efficient degradation of gluten by a prolyl endoprotease in a gastrointestinal model: implications for coeliac disease (2008), Gut, 57, 25-32.
    View publication on PubMed
Search for more literature for 3.4.21.26

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
gluten + H2O Aspergillus niger degradation of gluten in the human host's intestinal tract, i.e. stomach, duodenum, jejunum, and ileum ?
-
 ?
gluten peptides + H2O Aspergillus niger degradation of gluten peptides in the human host's intestinal tract, i.e. stomach, duodenum, jejunum, and ileum ?
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus niger
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Gly-Pro-4-nitroanilide + H2O
-
 Aspergillus niger benzyloxycarbonyl-Gly-Pro + 4-nitroaniline
-
 ?
gluten + H2O degradation of gluten in the human host's intestinal tract, i.e. stomach, duodenum, jejunum, and ileum Aspergillus niger ?
-
 ?
gluten + H2O determination of activity in a dynamic system that closely mimics the human gastrointestinal tract, overview Aspergillus niger ?
-
 ?
gluten peptides + H2O degradation of gluten peptides in the human host's intestinal tract, i.e. stomach, duodenum, jejunum, and ileum Aspergillus niger ?
-
 ?
gluten peptides + H2O determination of activity in a dynamic system that closely mimics the human gastrointestinal tract, overview Aspergillus niger ?
-
 ?

Synonyms

Synonyms Comment Organism
post-proline cutting enzyme
-
 Aspergillus niger
prolyl endoprotease
-
 Aspergillus niger

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Aspergillus niger

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.6
-
 assay at Aspergillus niger