Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.19.12 extracted from

  • Diaz-Arrastia, R.; Wang, K.K.; Papa, L.; Sorani, M.D.; Yue, J.K.; Puccio, A.M.; McMahon, P.J.; Inoue, T.; Yuh, E.L.; Lingsma, H.F.; Maas, A.I.; Valadka, A.B.; Okonkwo, D.O.; Manley, G.T.; Manley, G.T.
    Acute biomarkers of traumatic brain injury: relationship between plasma levels of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein (2014), J. Neurotrauma, 31, 19-25.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.19.12

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
UCH-L1
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function both biomarkers UCH-L1 and glial fibrillary acidic protein(GFAP) discriminate between traumatic brain injury (TBI) patients with intracranial lesions on CT scan from those without such lesions. GFAP measures are significantly more sensitive and specific than UCH-L1. The addition of UCH-L1 values marginally improved upon GFAP alone in predicting dichotomized Glasgow Outcome Scale Extended (GOS-E) at 3 months after injury Homo sapiens