Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ubiquitin | - |
Homo sapiens | |
Ubiquitin aldehyde | inhibition mechanism | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinectis | Homo sapiens | |
0.000035 | - |
ubiquitinyl-7-amido-4-methylcoumarin | pH 7.5, 25°C | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | UCH-L1 is involved in Parkinson's disease | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Homo sapiens | P09936 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | UCH-L1 is involved in Parkinson's disease | Homo sapiens | ? | - |
? | |
ubiquitin-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ubiquitin + 7-amino-4-methylcoumarin | - |
ir | |
ubiquitin-alcohol + H2O | - |
Homo sapiens | ubiquitin + alcohol | - |
ir | |
ubiquitinyl-7-amido-4-methylcoumarin + H2O | mechanistic studies | Homo sapiens | ubiquitin + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | the enzyme belongs to the family of ubiquitin-specific processing enzymes | Homo sapiens |
ubiquitin C-terminal hydrolase L1 | - |
Homo sapiens |
UCH-L1 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Homo sapiens |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
analysis of temperature dependence of the reaction, overview | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
ubiquitinyl-7-amido-4-methylcoumarin | pH 7.5, 25°C | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 9 | analysis of pH dependence of the reaction, overview | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000001 | - |
Ubiquitin aldehyde | below, pH 7.5, 25°C, inhibition kinectis | Homo sapiens | |
0.00014 | - |
ubiquitin | - |
Homo sapiens |