Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | - |
Mus musculus | - |
serum | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
ACE2 | - |
Mus musculus |
angiotensin converting enzyme 2 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | infection with highly pathogenic avian influenza A H5N1 virus results in downregulation of angiotensin-converting enzyme 2 (ACE2) expression in the lung | down |
Mus musculus | infection with highly pathogenic avian influenza A H5N1 virus results in increased expression of angiotensin-converting enzyme 2 (ACE2) in serum | up |
General Information | Comment | Organism |
---|---|---|
malfunction | genetic inactivation of ACE2 causes severe lung injury in H5N1-challenged mice. Administration of recombinant ACE2 ameliorates avian influenza H5N1 virus-induced lung injury in mice | Mus musculus |
physiological function | ACE2 plays an important role in H5N1 virus-induced ALI | Mus musculus |