Inhibitors | Comment | Organism | Structure |
---|---|---|---|
angiotensin II C-terminal analogs | screening of a library of angiotensin II C-terminal analogs identifies a number of tetrapeptides with increased ACE2 inhibition, and identifies residues critical to the binding of angiotensin II to the active site of ACE2 | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | zinc carboxypeptidase | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin II + H2O | Homo sapiens | the enzyme is involved in the renin angiotensin system | angiotensin-(1-7) + L-Phe | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | the enzyme is upregulated in cardiovascular disease | Homo sapiens | - |
liver | the enzyme is upregulated in fibrotic liver | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin II + H2O | - |
Homo sapiens | angiotensin-(1-7) + L-Phe | - |
? | |
angiotensin II + H2O | the enzyme is involved in the renin angiotensin system | Homo sapiens | angiotensin-(1-7) + L-Phe | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACE2 | - |
Homo sapiens |
angiotensin II converting enzyme 2 | - |
Homo sapiens |