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Literature summary for 1.3.1.79 extracted from

  • Waldner-Sander, S.; Keller, B.; Keller, E.; Lingens, F.
    Zur Biosynthese von Phenylalanin und Tyrosin bei Flavobakterien (1983), Hoppe-Seyler's Z. Physiol. Chem., 364, 1467-1473.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
L-tyrosine slightly enhanced activity Myroides odoratus
L-tyrosine slightly enhanced activity Flavobacterium suaveolens
phenylalanine slightly enhanced activity Myroides odoratus
phenylalanine slightly enhanced activity Flavobacterium suaveolens

Inhibitors

Inhibitors Comment Organism Structure
L-phenylalanine
-
Agromyces mediolanus
L-phenylalanine
-
Empedobacter brevis
L-phenylalanine
-
Flavobacterium aquatile
L-phenylalanine
-
[Flavobacterium] lutescens
L-phenylalanine
-
Flavobacterium paucimobilis
L-phenylalanine
-
Novosphingobium capsulatum
L-phenylalanine
-
Sphingomonas paucimobilis
L-tyrosine
-
Agromyces mediolanus
L-tyrosine
-
Empedobacter brevis
L-tyrosine
-
Flavobacterium aquatile
L-tyrosine
-
[Flavobacterium] lutescens
L-tyrosine
-
Flavobacterium paucimobilis
L-tyrosine
-
Novosphingobium capsulatum
L-tyrosine
-
Sphingomonas paucimobilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arogenate + NAD+ Sphingomonas paucimobilis i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ Novosphingobium capsulatum i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ Flavobacterium aquatile i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ Empedobacter brevis i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ Myroides odoratus i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ Flavobacterium suaveolens i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ [Flavobacterium] lutescens i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ Flavobacterium paucimobilis i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ Agromyces mediolanus i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine L-tyrosine + NADH + CO2
-
?

Organism

Organism UniProt Comment Textmining
Agromyces mediolanus
-
-
-
Empedobacter brevis
-
-
-
Flavobacterium aquatile
-
-
-
Flavobacterium paucimobilis
-
-
-
Flavobacterium suaveolens
-
-
-
Myroides odoratus
-
-
-
Novosphingobium capsulatum
-
-
-
Sphingomonas paucimobilis
-
-
-
[Flavobacterium] lutescens
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [Āµmol/min/mg] Specific Activity Maximum [Āµmol/min/mg] Comment Organism
additional information
-
-
Sphingomonas paucimobilis
additional information
-
-
Novosphingobium capsulatum
additional information
-
-
Flavobacterium aquatile
additional information
-
-
Empedobacter brevis
additional information
-
-
Myroides odoratus
additional information
-
-
Flavobacterium suaveolens
additional information
-
-
[Flavobacterium] lutescens
additional information
-
-
Flavobacterium paucimobilis
additional information
-
-
Agromyces mediolanus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arogenate + NAD(P)+
-
Sphingomonas paucimobilis L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD(P)+
-
Novosphingobium capsulatum L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD(P)+
-
Flavobacterium aquatile L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD(P)+
-
Empedobacter brevis L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD(P)+
-
Myroides odoratus L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD(P)+
-
Flavobacterium suaveolens L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD(P)+
-
[Flavobacterium] lutescens L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD(P)+
-
Flavobacterium paucimobilis L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD(P)+
-
Agromyces mediolanus L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine Sphingomonas paucimobilis L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine Novosphingobium capsulatum L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine Flavobacterium aquatile L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine Empedobacter brevis L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine Myroides odoratus L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine Flavobacterium suaveolens L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine [Flavobacterium] lutescens L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine Flavobacterium paucimobilis L-tyrosine + NADH + CO2
-
?
L-arogenate + NAD+ i.e. 3-(1-carboxy-4-hydroxycyclohexa-2,5-dien-1-yl)-L-alanine, final biosynthetic step to tyrosine Agromyces mediolanus L-tyrosine + NADH + CO2
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Sphingomonas paucimobilis
NAD+ NADP+ is a better electron acceptor than NAD+ Novosphingobium capsulatum
NAD+ NADP+ is a better electron acceptor than NAD+ Flavobacterium aquatile
NAD+ NADP+ is a better electron acceptor than NAD+ Empedobacter brevis
NAD+ NADP+ is a better electron acceptor than NAD+ Myroides odoratus
NAD+ NADP+ is a better electron acceptor than NAD+ Flavobacterium suaveolens
NAD+ NADP+ is a better electron acceptor than NAD+ [Flavobacterium] lutescens
NAD+ NADP+ is a better electron acceptor than NAD+ Flavobacterium paucimobilis
NAD+ NADP+ is a better electron acceptor than NAD+ Agromyces mediolanus
NADP+
-
Sphingomonas paucimobilis
NADP+ NADP+ is a better electron acceptor than NAD+ Novosphingobium capsulatum
NADP+ NADP+ is a better electron acceptor than NAD+ Flavobacterium aquatile
NADP+ NADP+ is a better electron acceptor than NAD+ Empedobacter brevis
NADP+ NADP+ is a better electron acceptor than NAD+ Myroides odoratus
NADP+ NADP+ is a better electron acceptor than NAD+ Flavobacterium suaveolens
NADP+ NADP+ is a better electron acceptor than NAD+ [Flavobacterium] lutescens
NADP+ NADP+ is a better electron acceptor than NAD+ Flavobacterium paucimobilis
NADP+ NADP+ is a better electron acceptor than NAD+ Agromyces mediolanus