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Literature summary for 1.2.7.4 extracted from
- Structural basis of cyanide inhibition of Ni, Fe-containing carbon monoxide dehydrogenase (2009), J. Am. Chem. Soc., 131, 9922-9923.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cyanide | slow binding inhibitor of CODH | Carboxydothermus hydrogenoformans |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | CODHII contains iron, the active site of CODH contains a [NiFe4S4OHx] cluster known as C-cluster | Carboxydothermus hydrogenoformans | |
| Ni2+ | CODHII contains nickel, the active site of CODH contains a [NiFe4S4OHx] cluster known as C-cluster | Carboxydothermus hydrogenoformans | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CO + H2O + acceptor | Carboxydothermus hydrogenoformans | - |
CO2 + reduced acceptor | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Carboxydothermus hydrogenoformans | Q9F8A8 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CO + H2O + acceptor | - |
Carboxydothermus hydrogenoformans | CO2 + reduced acceptor | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CODHII | - |
Carboxydothermus hydrogenoformans |
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