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Literature summary for 1.17.7.4 extracted from

  • Cheng, Q.; Tong, Y.; Wang, Z.; Su, P.; Gao, W.; Huang, L.
    Molecular cloning and functional identification of a cDNA encoding 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from Tripterygium wilfordii (2017), Acta Pharm. Sin. B, 7, 208-214 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.17.7.4

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli DH5alpha cells Tripterygium wilfordii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + reduced ferredoxin [iron-sulfur] cluster + H+ Tripterygium wilfordii
-
 dimethylallyl diphosphate + oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + reduced ferredoxin [iron-sulfur] cluster + H+ Tripterygium wilfordii
-
 isopentenyl diphosphate + oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Tripterygium wilfordii A0A088GJ08
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + reduced ferredoxin [iron-sulfur] cluster + H+
-
 Tripterygium wilfordii dimethylallyl diphosphate + oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + reduced ferredoxin [iron-sulfur] cluster + H+
-
 Tripterygium wilfordii isopentenyl diphosphate + oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?

Subunits

Subunits Comment Organism
? x * 52100, calculated from amino acid sequence Tripterygium wilfordii

Synonyms

Synonyms Comment Organism
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
-
 Tripterygium wilfordii
HDR
-
 Tripterygium wilfordii

pI Value

Organism Comment pI Value Maximum pI Value
Tripterygium wilfordii calculated from amino acid sequence
-
 5.6

Expression

Organism Comment Expression
Tripterygium wilfordii enzyme expression is induced by methyl jasmonate reaching the highest level after 1 h up