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Literature summary for 1.16.3.1 extracted from

  • Hellman, N.E.; Kono, S.; Mancini, G.M.; Hoogeboom, A.J.; de Jong, G.J.; Gitlin, J.D.
    Mechanisms of copper incorporation into human ceruloplasmin (2002), J. Biol. Chem., 277, 46632-46638.
    View publication on PubMed
Search for more literature for 1.16.3.1

Cloned(Commentary)

Cloned (Comment) Organism
gene sequencing and site-directed mutagenesis Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Cu2+
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
85000
-
-
 Saccharomyces cerevisiae
85000
-
 holoceruloplasmin, SDS-PAGE Homo sapiens
135000
-
 apoprotein, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fe2+ + H+ + O2 Saccharomyces cerevisiae
-
 Fe3+ + H2O
-
 ?
Fe2+ + H+ + O2 Homo sapiens multicopper oxidase essential for normal iron homeostasis Fe3+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-
Saccharomyces cerevisiae
-
 yeast
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Homo sapiens
-
leukocyte
-
 Homo sapiens
-
plasma
-
 Homo sapiens
-
plasma
-
 Saccharomyces cerevisiae
-
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fe2+ + H+ + O2
-
 Homo sapiens Fe3+ + H2O
-
 ?
Fe2+ + H+ + O2
-
 Saccharomyces cerevisiae Fe3+ + H2O
-
 ?
Fe2+ + H+ + O2 multicopper oxidase essential for normal iron homeostasis Homo sapiens Fe3+ + H2O
-
 ?

Synonyms

Synonyms Comment Organism
Fet3
-
 Saccharomyces cerevisiae