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Literature summary for 1.16.3.1 extracted from

  • Topham, R.W.; Jackson, M.R.; Joslin, S.A.; Walker, M.C.
    Studies of the ferroxidase activity of native and chemically modified xanthine oxidoreductase (1986), Biochem. J., 235, 39-44.
    View publication on PubMed
Search for more literature for 1.16.3.1

Inhibitors

Inhibitors Comment Organism Structure
catalase catalase in the assay system results in little inhibition of the ferroxidase activity of xanthine oxidoreductase Bos taurus
Superoxide dismutase superoxide dismutase in the assay system results in little inhibition of the ferroxidase activity of xanthine oxidoreductase Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0006
-
 Fe2+ pH 6.5, 30°C, 2 Km-values: 0.0006 and 0.050 mM Homo sapiens
0.009
-
 O2
-
 Homo sapiens
0.046
-
 Fe2+ xanthine oxidoreductase with ferroxidase activity Bos taurus
0.05
-
 O2 xanthine oxidoreductase with ferroxidase activity Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fe2+ + H+ + O2 Homo sapiens
-
 Fe3+ + H2O
-
 ?
Fe2+ + H+ + O2 Bos taurus
-
 Fe3+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
 human
-

Source Tissue

Source Tissue Comment Organism Textmining
milk
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fe2+ + H+ + O2
-
 Homo sapiens Fe3+ + H2O
-
 ?
Fe2+ + H+ + O2
-
 Bos taurus Fe3+ + H2O
-
 ?

Synonyms

Synonyms Comment Organism
xanthine oxidoreductase
-
 Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
 Homo sapiens
7.4
-
 xanthine oxidoreductase with ferroxidase activity Bos taurus