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Literature summary for 1.14.19.3 extracted from

  • Dong, Y.; Wang, S.; You, C.; Xie, D.; Jiang, Q.; Li, Y.
    Hepatocyte nuclear factor 4alpha (Hnf4alpha) is involved in transcriptional regulation of DELTA6/DELTA5 fatty acyl desaturase (Fad) gene expression in marine teleost Siganus canaliculatus (2020), Comp. Biochem. Physiol. B, 239, 110353.
    View publication on PubMed
Search for more literature for 1.14.19.3

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ Siganus canaliculatus
-
 stearidonoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
 ?
linoleoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ Siganus canaliculatus
-
 gamma-linolenoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Siganus canaliculatus
-
 rabbitfish
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
 Siganus canaliculatus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-linolenoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+
-
 Siganus canaliculatus stearidonoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
 ?
linoleoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+
-
 Siganus canaliculatus gamma-linolenoyl-CoA + 2 ferricytochrome b5 + 2 H2O
-
 ?

Synonyms

Synonyms Comment Organism
DELTA6/DELTA5 fad
-
 Siganus canaliculatus
DELTA6/DELTA5 fatty acyl desaturase
-
 Siganus canaliculatus

Expression

Organism Comment Expression
Siganus canaliculatus enzyme mRNA expression levels are significantly increased in after treatment with hepatocyte nuclear factor 4alpha agonists (Alverine and Benfluorex) or its mRNA overexpression up