Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.5.13 extracted from

  • Knorr, S.; Sinn, M.; Galetskiy, D.; Williams, R.; Wang, C.; Mueller, N.; Mayans, O.; Schleheck, D.; Hartig, J.
    Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate (2018), Nat. Commun., 9, 5071.
    View publication on PubMed
Search for more literature for 1.1.5.13

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic membrane
-
 Escherichia coli
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-2-hydroxyglutarate + a quinone Escherichia coli
-
 2-oxoglutarate + a quinol
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-2-hydroxyglutarate + a quinone
-
 Escherichia coli 2-oxoglutarate + a quinol
-
 ?
L-2-hydroxyglutarate + menaquinone-4
-
 Escherichia coli 2-oxoglutarate + menaquinol-4
-
 ?
L-2-hydroxyglutarate + ubiquinone-1
-
 Escherichia coli 2-oxoglutarate + ubiquinol-1
-
 ?

Synonyms

Synonyms Comment Organism
L-2-hydroxyglutarate dehydrogenase
-
 Escherichia coli
L2HG dehydrogenase
-
 Escherichia coli
L2HG:quinone oxidoreductase
-
 Escherichia coli
lhgO
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
FAD dependent on Escherichia coli