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Literature summary for 1.1.1.7 extracted from
- The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate dehydrogenase (1959), J. Biol. Chem., 234, 1641-1646.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Br- | - |
Oryctolagus cuniculus |  |
| formate | - |
Oryctolagus cuniculus | |
| SO32- | - |
Oryctolagus cuniculus | |
| SO42- | - |
Oryctolagus cuniculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 5.5 | - |
Hydroxyacetone phosphate | - |
Oryctolagus cuniculus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| propane-1,2-diol-1-phosphate + NAD+ | Oryctolagus cuniculus | - |
hydroxyacetone phosphate + NADH | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
rabbit | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| muscle | - |
Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.3 | - |
0.1-0.43 | Oryctolagus cuniculus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, dialyzed against Tris-buffer, pH 7.7, 80% loss of activity in 1 month | Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hydroxyacetone phosphate + NADH | - |
Oryctolagus cuniculus | propane-1,2-diol-1-phosphate + NAD+ | - |
r | |
| propane-1,2-diol-1-phosphate + NAD+ | - |
Oryctolagus cuniculus | hydroxyacetone phosphate + NADH | - |
r | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
dehydrogenation of propane-1,2-diol 1-phosphate has alkaline pH-optimum | Oryctolagus cuniculus |
| 7.7 | - |
hydroxyacetone phosphate reduction | Oryctolagus cuniculus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.4 | 9.6 | hydroxyacetone phosphate reduction, values strongly dependent on buffer system | Oryctolagus cuniculus |
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