Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bis(2-butoxyethyl) phthalate | potent inhibitor of testis 17beta-hydroxysteroid dehydrogenase type 3, additionally inhibits 3beta-hydroxysteriod dehydrogenase | Homo sapiens | |
bis(2-butoxyethyl) phthalate | potent inhibitor of testis 17beta-hydroxysteroid dehydrogenase type 3, additionally inhibits 3beta-hydroxysteriod dehydrogenase | Rattus norvegicus | |
dicyclohexyl phthalate | potent inhibitor of testis 17beta-hydroxysteroid dehydrogenase type 3, additionally inhibits 3beta-hydroxysteriod dehydrogenase | Homo sapiens | |
dicyclohexyl phthalate | potent inhibitor of testis 17beta-hydroxysteroid dehydrogenase type 3, additionally inhibits 3beta-hydroxysteriod dehydrogenase | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P37058 | - |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
testis | - |
Homo sapiens | - |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0055 | - |
dicyclohexyl phthalate | isoform 17beta-hydroxysteroid dehydrogenase type 3, pH 7.4, 37°C | Homo sapiens | |
0.0085 | - |
dicyclohexyl phthalate | isoform 17beta-hydroxysteroid dehydrogenase type 3, pH 7.4, 37°C | Rattus norvegicus | |
0.0165 | - |
dicyclohexyl phthalate | isoform 3beta-hydroxysteriod dehydrogenase, pH 7.4, 37°C | Rattus norvegicus | |
0.017 | - |
bis(2-butoxyethyl) phthalate | isoform 17beta-hydroxysteroid dehydrogenase type 3 , pH 7.4, 37°C | Homo sapiens | |
0.0219 | - |
dicyclohexyl phthalate | isoform 3beta-hydroxysteriod dehydrogenase, pH 7.4, 37°C | Homo sapiens | |
0.0285 | - |
bis(2-butoxyethyl) phthalate | isoform 17beta-hydroxysteroid dehydrogenase type 3 , pH 7.4, 37°C | Rattus norvegicus | |
0.0335 | - |
bis(2-butoxyethyl) phthalate | isoform 3beta-hydroxysteriod dehydrogenase , pH 7.4, 37°C | Homo sapiens | |
0.05 | - |
bis(2-butoxyethyl) phthalate | isoform 3beta-hydroxysteriod dehydrogenase , pH 7.4, 37°C | Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0082 | - |
isoform 17beta-hydroxysteroid dehydrogenase type 3, pH 7.4, 37°C | Homo sapiens | dicyclohexyl phthalate | |
0.0233 | - |
isoform 17beta-hydroxysteroid dehydrogenase type 3 , pH 7.4, 37°C | Homo sapiens | bis(2-butoxyethyl) phthalate | |
0.0247 | - |
isoform 3beta-hydroxysteriod dehydrogenase, pH 7.4, 37°C | Rattus norvegicus | dicyclohexyl phthalate | |
0.0255 | - |
isoform 3beta-hydroxysteriod dehydrogenase, pH 7.4, 37°C | Homo sapiens | dicyclohexyl phthalate | |
0.0302 | - |
isoform 17beta-hydroxysteroid dehydrogenase type 3 , pH 7.4, 37°C | Rattus norvegicus | bis(2-butoxyethyl) phthalate | |
0.0503 | - |
isoform 3beta-hydroxysteriod dehydrogenase , pH 7.4, 37°C | Homo sapiens | bis(2-butoxyethyl) phthalate | |
0.0825 | - |
isoform 3beta-hydroxysteriod dehydrogenase , pH 7.4, 37°C | Rattus norvegicus | bis(2-butoxyethyl) phthalate | |
0.09 | - |
isoform 17beta-hydroxysteroid dehydrogenase type 3, pH 7.4, 37°C | Rattus norvegicus | dicyclohexyl phthalate |