Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-[(4-nitrophenyl)amino]benzoic acid | 94fold selectivity for the inhibition of isoform AKR1C3 over AKR1C2 | Homo sapiens | |
3-[[4-(methoxymethyl)phenyl]amino]benzoic acid | 360fold selectivity for the inhibition of isoform AKR1C3 over AKR1C2 | Homo sapiens | |
3-[[4-(trifluoromethyl)phenyl]amino]benzoic acid | 250fold selectivity for the inhibition of isoform AKR1C3 over AKR1C2 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P42330 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-tetralol + NADP+ | - |
Homo sapiens | ? + NADPH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AKR1C3 | - |
Homo sapiens |
type 5 beta-hydroxysteroid dehydrogenase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000036 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-[(4-nitrophenyl)amino]benzoic acid | |
0.000054 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-[[4-(methoxymethyl)phenyl]amino]benzoic acid | |
0.000062 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-[[4-(trifluoromethyl)phenyl]amino]benzoic acid |