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Literature summary for 1.1.1.51 extracted from
- Inhibitors of 17?-hydroxysteroid dehydrogenase type 1, 2 and 14 Structures, biological activities and future challenges (2019), Mol. Cell. Endocrinol., 489, 66-81.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | 17beta-HSD1 and 17beta-HSD2 inhibitor structures and their biological activities are reviewed | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| estrone + NAD(P)H + H+ | Homo sapiens | the product 17beta-estradiol plays a central role in the etiology of estrogen dependent diseases | 17beta-estradiol + NAD(P)+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P14061 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| estrone + NAD(P)H + H+ | the product 17beta-estradiol plays a central role in the etiology of estrogen dependent diseases | Homo sapiens | 17beta-estradiol + NAD(P)+ | - |
? | |
| estrone + NAD(P)H + H+ | - |
Homo sapiens | 17beta-estradiol + NAD(P)+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 17beta-HSD1 | - |
Homo sapiens |
| 17beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
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