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Literature summary for 1.1.1.49 extracted from

  • Wang, X.T.; Chan, T.F.; Lam, V.M.; Engel, P.C.
    What is the role of the second, "structural" NADP+ binding site in human glucose 6-phosphate dehydrogenase? (2008), Protein Sci., 17, 1403-1411.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
10000
-
dimeric apoenzyme, gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P11413
-
-

Synonyms

Synonyms Comment Organism
G6PD
-
Homo sapiens

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
4
-
inactivation at 4°C is partially reversed at room temperature, especially with added NADP+ Homo sapiens
37
-
the stripped enzyme, much less stable than holoenzyme, inactivates irreversibly within 2 d Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADP+ the enzyme contains 1 mol NADP+ per subunit. Apoenzyme, devoid of bound NADP+, is still fully active Homo sapiens