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Literature summary for 1.1.1.42 extracted from
- Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas (2009), J. Clin. Oncol., 27, 4150-4154.
Application
| Application | Comment | Organism |
|---|---|---|
| diagnostics | IDH1 codon 132 mutation is an important prognostic biomarker in gliomas. IDH1 mutation predicts outcome in grade 2, 3, and 4 gliomas | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| IDH1, genotyping and genomic profile, overview | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | 1p19q deletion correlates with pure oligodendrogliomas | Homo sapiens |
| R132C | naturally occuring mutation C394T, genotyping in glioma samples, overview | Homo sapiens |
| R132G | naturally occuring mutation C394G, genotyping in glioma samples, overview | Homo sapiens |
| R132H | naturally occuring mutation G395A, genotyping in glioma samples, overview | Homo sapiens |
| R132L | naturally occuring mutation G395T, genotyping in glioma samples, overview | Homo sapiens |
| R132S | naturally occuring mutation C394A, genotyping in glioma samples, overview | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| glioma cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| IDH1 | - |
Homo sapiens |
| isocitrate dehydrogenase 1 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | IDH1 mutation predicts outcome in grade 2, 3, and 4 gliomas | Homo sapiens |
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