Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.42 extracted from

  • McKinnon, D.J.; Brzezowski, P.; Wilson, K.E.; Gray, G.R.
    Mitochondrial and chloroplastic targeting signals of NADP+-dependent isocitrate dehydrogenase (2009), Biochem. Cell Biol., 87, 963-974.
    View publication on PubMed
Search for more literature for 1.1.1.42

Cloned(Commentary)

Cloned (Comment) Organism
NADP+-ICDH contains two different translational ATG start sites, fusion of mitochondrial and chloroplastic targeting signals to YFP reporter, and transient expression in Nicotiana tabacum using Agrobacterium tumefaciens transfection method. The chloroplast-tageting signal constructs are localizes in the chloroplast, while the mitochondrial constructs are localized in either in mitochondria and chloroplasts, due to an 50 amino acid additional part that is added in expression in cultivars Xanthi and Petit Havana Nicotiana tabacum

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
 Nicotiana tabacum 9507
-
mitochondrion
-
 Nicotiana tabacum 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isocitrate + NADP+ Nicotiana tabacum
-
 2-oxoglutarate + NADPH + H+ + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum O65853
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Nicotiana tabacum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isocitrate + NADP+
-
 Nicotiana tabacum 2-oxoglutarate + NADPH + H+ + CO2
-
 ?

Synonyms

Synonyms Comment Organism
NADP+-dependent isocitrate dehydrogenase
-
 Nicotiana tabacum
NADP+-ICDH belongs to a mutli-isoenzyme family Nicotiana tabacum

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Nicotiana tabacum