Literature summary for 1.1.1.42 extracted from

Lee, J.H.; Kim, S.Y.; Kil, I.S.; Park, J.W.
Regulation of ionizing radiation-induced apoptosis by mitochondrial NADP+-dependent isocitrate dehydrogenase (2007), J. Biol. Chem., 282, 13385-13394.

Search for more literature for 1.1.1.42

Application

Application	Comment	Organism
medicine	transfection of HeLa cells with an NADP+-dependent isocitrate dehydrogenase small interfering RNA decreased the activity of IDPm, enhancing the susceptibility of radiation-induced apoptosis. The effect of NADP+-dependent isocitrate dehydrogenaseIDPm small interfering RNA on HeLa cells offers the possibility of developing a modifier of radiation therapy	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P48735	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
U-937 cell	NADP+-dependent isocitrate dehydrogenase may play an important role in regulating the apoptosis induced by ionizing radiation	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
IDPm	-	Homo sapiens
NADP+-dependent isocitrate dehydrogenase	-	Homo sapiens

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Release 2023.1 (January 2023)