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Literature summary for 1.1.1.41 extracted from
- Novel insights into the contributions of isocitrate dehydrogenases to the Krebs cycle from patients with retinitis pigmentosa (2008), Nat. Genet., 40, 1230-1234.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| L98P | the mutation is associated with retinitis pigmentosa | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O43837 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lymphoblast | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DL-isocitrate + NAD+ | - |
Homo sapiens | 2-oxoglutarate + CO2 + NADH | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NAD-IDH | - |
Homo sapiens |
| NAD-specific isocitrate dehydrogenase | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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