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Literature summary for 1.1.1.37 extracted from

  • Sundaram, T.K.; Wright, I.P.; Wilkinson, A.E.
    Malate dehydrogenase from thermophilic and mesophilic bacteria. Molecular size, subunit structure, amino acid composition, immunochemical homology, and catalytic activity (1980), Biochemistry, 19, 2017-2022.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Sus scrofa 5739
-
mitochondrion
-
Neurospora crassa 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
32000
-
4 * 32000, SDS-PAGE Laceyella sacchari
34000
-
2 * 34000, SDS-PAGE Bacillus sp. (in: Bacteria)
34000
-
4 * 34000, SDS-PAGE Vogesella indigofera
35000
-
4 * 35000, SDS-PAGE Bacillus subtilis
35000
-
4 * 35000, SDS-PAGE Geobacillus stearothermophilus
35300
-
4 * 35300, SDS-PAGE [Bacillus] caldotenax
36000
-
2 * 36000, SDS-PAGE Thermus aquaticus
67000
-
-
Sus scrofa
67000
-
-
Neurospora crassa
67000
-
gel filtration Vogesella indigofera
70000
-
gel filtration Thermobifida fusca
71000
-
gel filtration Thermus aquaticus
79120
-
sedimentation equilibrium method Thermobifida fusca
85040
-
sedimentation equilibrium method Thermus aquaticus
124000
-
gel filtration [Bacillus] caldotenax
125000
-
gel filtration Laceyella sacchari
133600
-
sedimentation equilibrium method Laceyella sacchari
134900
-
sedimentation equlibrium method [Bacillus] caldotenax
135000
-
gel filtration Bacillus sp. (in: Bacteria)
137100
-
N.C.A. 1518 Ra2, N.C.A. 1503, sedimentation equilibrium method Geobacillus stearothermophilus
138000
-
N.C.A. 1518 Ra2, gel filtration Geobacillus stearothermophilus
138600
-
sedimentation equilibrium method Bacillus subtilis
140900
-
sedimentation equilibrium method Bacillus sp. (in: Bacteria)
142000
-
gel filtration Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
malate + NAD+ Thermus aquaticus
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Bacillus subtilis
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Escherichia coli
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Sus scrofa
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Geobacillus stearothermophilus
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Neurospora crassa
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Bacillus sp. (in: Bacteria)
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ [Bacillus] caldotenax
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Thermobifida fusca
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Vogesella indigofera
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Laceyella sacchari
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Thermus aquaticus YT-1
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Thermobifida fusca NCIB 11185
-
oxaloacetate + NADH + H+
-
r
malate + NAD+ Laceyella sacchari NCIB 10486
-
oxaloacetate + NADH + H+
-
r

Organism

Organism UniProt Comment Textmining
Bacillus sp. (in: Bacteria)
-
moderate thermophile, designated BI
-
Bacillus subtilis
-
-
-
Escherichia coli
-
-
-
Geobacillus stearothermophilus
-
N.C.A 1503, N.C.A. 1518 Ra2, 2184
-
Laceyella sacchari
-
N.C.I.B. 10486
-
Laceyella sacchari NCIB 10486
-
N.C.I.B. 10486
-
Neurospora crassa
-
-
-
Sus scrofa
-
pig
-
Thermobifida fusca
-
N.C.I.B. 11185
-
Thermobifida fusca NCIB 11185
-
N.C.I.B. 11185
-
Thermus aquaticus
-
-
-
Thermus aquaticus YT-1
-
-
-
Vogesella indigofera
-
-
-
[Bacillus] caldotenax
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
Thermus aquaticus oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Bacillus subtilis oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Escherichia coli oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Sus scrofa oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Geobacillus stearothermophilus oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Neurospora crassa oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Bacillus sp. (in: Bacteria) oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
[Bacillus] caldotenax oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Thermobifida fusca oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Vogesella indigofera oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Laceyella sacchari oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Thermus aquaticus YT-1 oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Thermobifida fusca NCIB 11185 oxaloacetate + NADH + H+
-
r
(S)-malate + NAD+
-
Laceyella sacchari NCIB 10486 oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Thermus aquaticus oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Bacillus subtilis oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Escherichia coli oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Sus scrofa oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Geobacillus stearothermophilus oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Neurospora crassa oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Bacillus sp. (in: Bacteria) oxaloacetate + NADH + H+
-
r
malate + NAD+
-
[Bacillus] caldotenax oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Thermobifida fusca oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Vogesella indigofera oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Laceyella sacchari oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Thermus aquaticus YT-1 oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Thermobifida fusca NCIB 11185 oxaloacetate + NADH + H+
-
r
malate + NAD+
-
Laceyella sacchari NCIB 10486 oxaloacetate + NADH + H+
-
r
oxaloacetate + NADH
-
Thermus aquaticus L-malate + NAD+
-
r
oxaloacetate + NADH
-
Bacillus subtilis L-malate + NAD+
-
r
oxaloacetate + NADH
-
Escherichia coli L-malate + NAD+
-
r
oxaloacetate + NADH
-
Sus scrofa L-malate + NAD+
-
r
oxaloacetate + NADH
-
Geobacillus stearothermophilus L-malate + NAD+
-
r
oxaloacetate + NADH
-
Neurospora crassa L-malate + NAD+
-
r
oxaloacetate + NADH
-
Bacillus sp. (in: Bacteria) L-malate + NAD+
-
r
oxaloacetate + NADH
-
[Bacillus] caldotenax L-malate + NAD+
-
r
oxaloacetate + NADH
-
Thermobifida fusca L-malate + NAD+
-
r
oxaloacetate + NADH
-
Vogesella indigofera L-malate + NAD+
-
r
oxaloacetate + NADH
-
Laceyella sacchari L-malate + NAD+
-
r
oxaloacetate + NADH
-
Thermus aquaticus YT-1 L-malate + NAD+
-
r
oxaloacetate + NADH
-
Thermobifida fusca NCIB 11185 L-malate + NAD+
-
r
oxaloacetate + NADH
-
Laceyella sacchari NCIB 10486 L-malate + NAD+
-
r

Subunits

Subunits Comment Organism
dimer
-
Sus scrofa
dimer
-
Vogesella indigofera
dimer 2 * 34000, SDS-PAGE Bacillus sp. (in: Bacteria)
dimer 2 * 36000, SDS-PAGE Thermus aquaticus
tetramer
-
Escherichia coli
tetramer
-
Bacillus sp. (in: Bacteria)
tetramer 4 * 34000, SDS-PAGE Vogesella indigofera
tetramer 4 * 35000, SDS-PAGE Bacillus subtilis
tetramer 4 * 35000, SDS-PAGE Geobacillus stearothermophilus
tetramer 4 * 32000, SDS-PAGE Laceyella sacchari
tetramer 4 * 35300, SDS-PAGE [Bacillus] caldotenax