Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.331 extracted from

  • Wankhede, D.P.; Biswas, D.K.; Rajkumar, S.; Sinha, A.K.
    Expressed sequence tags and molecular cloning and characterization of gene encoding pinoresinol/lariciresinol reductase from Podophyllum hexandrum (2013), Protoplasma, 250, 1239-1249 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene PhSDH, sequence comparisons, semiquantitative RT-PCR expression analysis Sinopodophyllum hexandrum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(-)-secoisolariciresinol + 2 NAD+ Sinopodophyllum hexandrum
-
(-)-matairesinol + 2 NADH + 2 H+
-
?

Organism

Organism UniProt Comment Textmining
Sinopodophyllum hexandrum A3F5F0 cvs. Yada and Jobrang
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Sinopodophyllum hexandrum
-
additional information expression pattern of PhSDH in different tissues and under abiotic stress, overview. PhSDH has the lowest expression in leaf compared to stem and root Sinopodophyllum hexandrum
-
rhizome
-
Sinopodophyllum hexandrum
-
root
-
Sinopodophyllum hexandrum
-
stem
-
Sinopodophyllum hexandrum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(-)-secoisolariciresinol + 2 NAD+
-
Sinopodophyllum hexandrum (-)-matairesinol + 2 NADH + 2 H+
-
?

Synonyms

Synonyms Comment Organism
PhSDH
-
Sinopodophyllum hexandrum

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Sinopodophyllum hexandrum

Expression

Organism Comment Expression
Sinopodophyllum hexandrum the enzyme expression is induced by wounding and methyl jasmonate, while UV light induces short peaks of the enzyme expression after 6 h intervals, expression pattern of PhSDH in different tissues and under abiotic stress, overview up

General Information

General Information Comment Organism
metabolism the enzyme is part of the podophyllotoxin, PPT, biosynthetic pathway, overview. Podophyllotoxin is an important aryltetralin lignan, that possesses antitumor and antihyperlipidemic activities Sinopodophyllum hexandrum