Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | no effect, no activation by cholestyramine | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | membrane-bound | Rattus norvegicus | 16020 | - |
microsome | - |
Rattus norvegicus | - |
- |
additional information | - |
Rattus norvegicus | - |
- |
peroxisome | - |
Rattus norvegicus | 5777 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | enzyme of cholesterol biosynthesis | ? | - |
? | |
additional information | Rattus norvegicus | enzyme of mevalonate pathway for biosynthesis of cholesterol from lanosterol | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male sprague-dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4,4-gem-dimethyl-5alpha-cholest-7-en-3-one + NADPH | - |
Rattus norvegicus | 4,4-gem-dimethyl-5alpha-cholest-7-en-3beta-ol + NADP+ | - |
? | |
additional information | enzyme of cholesterol biosynthesis | Rattus norvegicus | ? | - |
? | |
additional information | enzyme of mevalonate pathway for biosynthesis of cholesterol from lanosterol | Rattus norvegicus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |