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Literature summary for 1.1.1.245 extracted from

  • Trower, M.K.; Buckland, R.M.; Higgins, R.; Griffin, M.
    Isolation and characterization of a cyclohexane-metabolizing Xanthobacter sp. (1985), Appl. Environ. Microbiol., 49, 1282-1289.
    View publication on PubMedView publication on EuropePMC
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0013
-
 Cyclohexanol pH 10.3 Xanthobacter sp.
0.41
-
 Cyclohexane-1,2-diol pH 10.3 Xanthobacter sp.
0.5
-
 Cyclohexane-1,3-diol pH 10.3 Xanthobacter sp.
0.59
-
 Cyclohexane-1,4-diol pH 10.3 Xanthobacter sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cyclohexanol + NAD+ Xanthobacter sp. metabolism of cyclohexane cyclohexanone + NADH
-
 r

Organism

Organism UniProt Comment Textmining
Xanthobacter sp.
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.87
-
-
 Xanthobacter sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclohexan-1,2-diol + NAD+
-
 Xanthobacter sp. cyclohexane-1,2-dione + NADH
-
 ?
cyclohexane-1,3-diol + NAD+
-
 Xanthobacter sp. cyclohexane-1,3-dione + NADH
-
 ?
cyclohexane-1,4-diol + NAD+
-
 Xanthobacter sp. cyclohexane-1,4-dione + NADH
-
 ?
cyclohexanol + NAD+ preferred substrate Xanthobacter sp. cyclohexanone + NADH
-
 ?
cyclohexanol + NAD+ metabolism of cyclohexane Xanthobacter sp. cyclohexanone + NADH
-
 r
additional information cyclohexane-1,2-dione is not oxidized with NAD+ Xanthobacter sp. additional information
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10.1 10.5 oxidation of alcohol Xanthobacter sp.

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Xanthobacter sp.
NADP+ weaker activity than with NAD+ Xanthobacter sp.