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Literature summary for 1.1.1.21 extracted from

  • Petrash, J.M.; Tarle, I.; Wilson, D.K.; Quiocho, F.A.
    Aldose reductase catalysis and crystallography (1994), Diabetes, 43, 955-959.
    View publication on PubMed
Search for more literature for 1.1.1.21

Crystallization (Commentary)

Crystallization (Comment) Organism
structural model Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
zopolrestat
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35800
-
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Reaction

Reaction Comment Organism Reaction ID
alditol + NAD(P)+ = aldose + NAD(P)H + H+ reaction mechanism Homo sapiens
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alditol + NAD(P)+
-
 Homo sapiens aldose + NAD(P)H
-
 r
aldose + NAD(P)H wide specificity Homo sapiens alditol + NAD(P)+
-
 ?
D-glucose + NAD(P)H
-
 Homo sapiens sorbitol + NAD(P)+
-
 r

Subunits

Subunits Comment Organism
monomer 1 * 35800, SDS-PAGE Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Homo sapiens