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Literature summary for 1.1.1.208 extracted from

  • Kjonaas, R.; Martinkus-Taylor, C.; Croteau, R.
    Metabolism of monoterpenes: Conversion of l-menthone tol-menthole and d-neomenthol by stereospecific dehydrogenases from peppermint (Mentha piperita) leaves (1982), Plant Physiol., 69, 1013-1017.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
Hg2+ almost complete inhibition at 0.25 mM Mentha x piperita
iodoacetamide almost complete inhibition at 0.25 mM Mentha x piperita
N-ethylmaleimide almost complete inhibition at 0.25 mM Mentha x piperita
p-hydroxymercuribenzoate almost complete inhibition at 0.05 mM Mentha x piperita

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.022
-
 NADPH (-)-menthone Mentha x piperita

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 gel filtration Mentha x piperita

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(-)-menthone + NADPH + H+ Mentha x piperita ? (+)-neomenthol + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Mentha x piperita
-
 peppermint
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mentha x piperita

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(-)-menthone + NADPH + H+ ir Mentha x piperita (+)-neomenthol + NADP+
-
 ?
(-)-menthone + NADPH + H+ ? Mentha x piperita (+)-neomenthol + NADP+
-
 ?
d-isomenthone + NADPH ? Mentha x piperita d-isomenthol + NADP+
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
 (-)-menthone + NADPH Mentha x piperita

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Mentha x piperita