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Literature summary for 1.1.1.202 extracted from

  • Nemeth, A.; Kupcsulik, B.; Sevella, B.
    1,3-Propanediol oxidoreductase production with Klebsiella pneumoniae DSM2026 (2003), World J. Microbiol. Biotechnol., 19, 659-663.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
glycerol at concentrations around 16 g/l, regulation, overview Klebsiella pneumoniae

Application

Application Comment Organism
synthesis Klebsiella pneumoniae is used for production of 1,3-propanediol by the enzyme which is utilized in plastic industry Klebsiella pneumoniae

Inhibitors

Inhibitors Comment Organism Structure
glycerol at high concentration above 40 g/l, overview Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
propane-1,3-diol + NAD+ Klebsiella pneumoniae key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol 3-hydroxypropanal + NADH
-
?
propane-1,3-diol + NAD+ Klebsiella pneumoniae DSM 2026 key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol 3-hydroxypropanal + NADH
-
?

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
DSM2026
-
Klebsiella pneumoniae DSM 2026
-
DSM2026
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
propane-1,3-diol + NAD+
-
Klebsiella pneumoniae 3-hydroxypropanal + NADH
-
r
propane-1,3-diol + NAD+ key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol Klebsiella pneumoniae 3-hydroxypropanal + NADH
-
?
propane-1,3-diol + NAD+
-
Klebsiella pneumoniae DSM 2026 3-hydroxypropanal + NADH
-
r
propane-1,3-diol + NAD+ key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol Klebsiella pneumoniae DSM 2026 3-hydroxypropanal + NADH
-
?

Synonyms

Synonyms Comment Organism
1,3-propanediol oxidoreductase
-
Klebsiella pneumoniae
1,3-propanediol-oxidoreductase
-
Klebsiella pneumoniae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
assay at Klebsiella pneumoniae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
assay at Klebsiella pneumoniae

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Klebsiella pneumoniae
NADH
-
Klebsiella pneumoniae

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
12.09
-
glycerol pH 9.0, 25°C Klebsiella pneumoniae