Literature summary for 1.1.1.189 extracted from

Oshige, T.; Ohtsuka, T.; Mibe, M.; Nagai, K.; Yamaguchi, M.; Ikenoue, T.; Mori, N.
Effects of saturated fatty acids on prostaglandin E 9-keto-reductase (1992), Prostaglandins Leukot. Essent. Fatty Acids, 45, 245-247.

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Inhibitors

Inhibitors	Comment	Organism	Structure
palmitic acid	inhibits enzyme in dose-dependent manner	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate + NADP+	-	Homo sapiens	(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH + H+	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Homo sapiens

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Release 2023.1 (January 2023)