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Literature summary for 1.1.1.150 extracted from
- The stereospecificity of the enzymatic reduction of 21-dehydrocortisol by NADH (1975), J. Biol. Chem., 250, 7547-7553.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries aries | - |
sheep | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Ovis aries aries | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 11beta,17-dihydroxy-pregn-4-ene-3,20,21-trione + NADH | i.e. 21-dehydrocortisol, transfer of the hydrogen to the 21-pro-S position of cortisol | Ovis aries aries | 11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NAD+ | - |
? |  |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Ovis aries aries | |
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