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Literature summary for 1.1.1.145 extracted from

  • Ota, T.; Doi, M.; Yamazaki, F.; Yarimizu, D.; Okada, K.; Murai, I.; Hayashi, H.; Kunisue, S.; Nakagawa, Y.; Okamura, H.
    Angiotensin II triggers expression of the adrenal gland zona glomerulosa-specific 3beta-hydroxysteroid dehydrogenase isoenzyme through de novo protein synthesis of the orphan nuclear receptors NGFIB and NURR1 (2014), Mol. Cell. Biol., 34, 3880-3894.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens P14060
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-

Source Tissue

Source Tissue Comment Organism Textmining
NCI-H295R cell
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Homo sapiens
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zona glomerulosa
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Homo sapiens
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Synonyms

Synonyms Comment Organism
HSD3B1
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens isoform HSD3B1 is expressed specifically within the adrenal zona glomerulosa. Angiotensin II triggers expression of HSD3B1but not that of isoform HSD3B2 in adrenocortical H295R cells. The induction of HSD3B1 involves de novo protein synthesis of the nuclear orphan receptors NGFIB and NURR1 up