Any feedback?
Literature summary for 1.1.1.145 extracted from
- 3?-hydroxy-??-C??-steroid dehydrogenase/isomerase deficiency in a patient who underwent oral bile acid therapy for 10 years and delivered two healthy infants. (2010), Pediatr. Internat., 52, e192-e195.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | patient with inborn error of bile acid metabolism, that is, 3beta-hydroxy-DELTA5-C27-steroid dehydrogenase/isomerase deficienc, receives as treatment chenodeoxycholic acid and cholic acid, orally administered for 10 years. After the oral bile acid therapy, the biochemical liver function values and serum alanine aminotransferase and total bilirubin levels are maintained at normal levels, while the 3beta,7alpha-dihydroxy- and 3beta,7alpha,12alpha-trihydroxy-5-cholenoic acid levels significantly decrease. The patient gave birth to a healthy boy and a girl during the 10-year follow-up period | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
