Literature summary for 1.1.1.145 extracted from

Meffre, D.; Delespierre, B.; Gouezou, M.; Schumacher, M.; Stein, D.G.; Guennoun, R.
3beta-Hydroxysteroid dehydrogenase/5-ene-4-ene isomerase mRNA expression in rat brain: effect of pseudopregnancy and traumatic brain injury (2007), J. Steroid Biochem. Mol. Biol., 104, 293-300.

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Application

Application	Comment	Organism
medicine	twenty-four hours after bilateral contusion of the medial prefrontal cortex, similar levels of 3beta-hydroxysteroid dehydrogenase mRNA expression are observed in males and pseudopregnant females in the non-injured group, with a significant decrease in the 3beta-hydroxysteroid dehydrogenase mRNA expression in the contusion site within the frontal cortex in both males and pseudopregnant females. In all other regions analyzed, 3beta-hydroxysteroid dehydrogenase mRNA expression is not affected by traumatic brain injury and there is no difference between males and pseudopregnant females	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	P22071	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	twenty-four hours after bilateral contusion of the medial prefrontal cortex, similar levels of 3beta-hydroxysteroid dehydrogenase mRNA expression are observed in males and pseudopregnant females in the non-injured group, with a significant decrease in the 3beta-hydroxysteroid dehydrogenase mRNA expression in the contusion site within the frontal cortex in both males and pseudopregnant females. In all other regions analyzed, 3beta-hydroxysteroid dehydrogenase mRNA expression is not affected by traumatic brain injury and there is no difference between males and pseudopregnant females	Rattus norvegicus	-

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Release 2023.1 (January 2023)