Application | Comment | Organism |
---|---|---|
pharmacology | enzyme is a target for design and development of potent and specific structure-based inhibitors binding in the active site | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | modelling of structure-based inhibitor binding into the active site | Homo sapiens | |
n-butyric acid | binds to the active site of the enzyme, complex structure determination and analysis | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
brush border | - |
Homo sapiens | 5903 | - |
membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-xylulose + NADPH + H+ | Homo sapiens | part of the glucuronic acid pathway, enzyme may be involved in water reabsorption and cellular osmoregulation | L-xylitol + NADP+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
xylitol + NADP+ = L-xylulose + NADPH + H+ | active site structure | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-xylulose + NADPH + H+ | - |
Homo sapiens | L-xylitol + NADP+ | - |
r | |
L-xylulose + NADPH + H+ | part of the glucuronic acid pathway, enzyme may be involved in water reabsorption and cellular osmoregulation | Homo sapiens | L-xylitol + NADP+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
XR | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |