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Ligand (S)-3-sulfolactate Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
C3 H6 O6 S
(S)-3-sulfolactate
CQQGIWJSICOUON-UWTATZPHSA-N
Related pathways
MetaCyc
sulfolactate degradation I, sulfoquinovose degradation II, sulfoquinovose degradation III, sulfoquinovose degradation VI
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (3 results)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3-sulfopyruvate + NADPH + H+ = (2S)-3-sulfolactate + NADP+
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(2S)-3-sulfolactaldehyde + NAD+ + H2O = (2S)-3-sulfolactate + NADH + H+
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(2S)-3-sulfolactaldehyde + NADP+ + H2O = (2S)-3-sulfolactate + NADPH + H+
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Substrate in Enzyme-catalyzed Reactions (3 results)
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(2S)-3-sulfolactate + NAD+ = 3-sulfopyruvate + NADH + H+
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(S)-3-sulfolactate + NADP+ = 3-sulfopyruvate + NADPH + H+
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(2S)-3-sulfolactate + NADP+ = 3-sulfopyruvate + NADPH + H+
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Product in Enzyme-catalyzed Reactions (7 results)
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3-sulfopyruvate + NADH + H+ = (2S)-3-sulfolactate + NAD+
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3-sulfopyruvate + NADH + H+ = (S)-3-sulfolactate + NAD+
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3-sulfopyruvate + NADPH + H+ = (S)-3-sulfolactate + NADP+
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3-sulfopyruvate + NADH + H+ = (2S)-3-sulfolactate + NAD+
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3-sulfopyruvate + NADPH + H+ = (2S)-3-sulfolactate + NADP+
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(2S)-3-sulfolactaldehyde + NAD+ + H2O = (2S)-3-sulfolactate + NADH + H+
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(2S)-3-sulfolactaldehyde + NADP+ + H2O = (2S)-3-sulfolactate + NADPH + H+
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Enzyme Kinetic Parameters
KM Value (3 results)
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7
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apparent value, in 25 mM Tris buffer, pH 9.0 and 25°C
4.6
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70°C, pH 9.5, cofactor: NADP+
References & Links Literature References (2)
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Identification of an archaeal 2-hydroxy acid dehydrogenase catalyzing reactions involved in coenzyme biosynthesis in methanoarchaea
2000
Graupner, M.; Xu, H.; White, R.H.
J. Bacteriol.
182
3688-3692
Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase
2010
Denger, K.; Cook, A.M.
Microbiology
156
967-974
Links to other databases for (S)-3-sulfolactate
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