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Ligand red chlorophyll catabolite

Basic Ligand Information

Molecular Structure

Related pathways

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.3.7.12

red chlorophyll catabolite + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ = primary fluorescent chlorophyll catabolite + 2 oxidized ferredoxin [iron-sulfur] cluster

735913, 736215, 674404, 699585, 712769, 736949, 736960, 676395, 735438

-

1.3.7.12

red chlorophyll catabolite + reduced acceptor = primary fluorescent chlorophyll catabolite + oxidized acceptor

699585, 700695

-

1.3.7.12

2 entries

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

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Show Natural Product (3 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.15.17

pheophorbide a + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = red chlorophyll catabolite + 2 oxidized ferredoxin [iron-sulfur] cluster

-

-

1.3.1.8

primary fluorescent chlorophyll catabolite + NADP+ = red chlorophyll catabolite + NADPH + H+

-

-

1.3.7.12

primary fluorescent chlorophyll catabolite + NADP+ = red chlorophyll catabolite + NADPH + H+

-

-

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.3.7.12

red chlorophyll catabolite + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ = primary fluorescent chlorophyll catabolite + 2 oxidized ferredoxin [iron-sulfur] cluster

735913, 736215, 674404, 699585, 712769, 736949, 736960, 676395, 735438

-

1.3.7.12

red chlorophyll catabolite + reduced acceptor = primary fluorescent chlorophyll catabolite + acceptor

676565

-

1.3.7.12

red chlorophyll catabolite + reduced acceptor = primary fluorescent chlorophyll catabolite + oxidized acceptor

699585, 700695

-

1.3.7.12

3 entries

Product in Enzyme-catalyzed Reactions (4 results)

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Show Product (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.15.17

pheophorbide a + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = red chlorophyll catabolite + 2 oxidized ferredoxin [iron-sulfur] cluster

-

-

1.14.15.17

pheophorbide a + NADPH + H+ + O2 = red chlorophyll catabolite + NADP+

-

-

1.14.15.17

2 entries

1.3.1.8

primary fluorescent chlorophyll catabolite + NADP+ = red chlorophyll catabolite + NADPH + H+

-

-

1.3.7.12

primary fluorescent chlorophyll catabolite + NADP+ = red chlorophyll catabolite + NADPH + H+

-

-

3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

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Show 3D Structure of Enzyme-Ligand-Complex (PDB) (2 entries)

EC NUMBER

ENZYME 3D STRUCTURE

1.3.1.80

3AGA, 3D-view

1.3.1.80

3AGC, 3D-view

1.3.1.80

2 entries

Enzyme Kinetic Parameters

K_M Value (1 result)

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Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.3.7.12

0.6

-

-

676565

References & Links

Literature References (11)

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Show Reference (11 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

674404

9624113

The key step in chlorophyll breakdown in higher plants. Cleavage of pheophorbide a macrocycle by a monooxygenase

1998

Hörtensteiner, S.; Wüthrich, K.L.; Matile, P.; Ongania, K.H.; Kräutler, B.

J. Biol. Chem.

273

15335-15339

676395

-

Evolution of chlorophyll degradation: the significance of RCC reductase

2000

Hörtensteiner, S.; Rodoni, S.; Schellenberg, M.; Vicentini, F.; Nandi, O.I.; Qui, Y.L.; Matile, P.

Plant Biol.

2

63-67

676565

12223836

Partial purification and characterization of red chlorophyll catabolite reductase, a stroma protein involved in chlorophyll breakdown

1997

Rodoni, S.; Vicentini, F.; Schellenberg, M.; Matile, P.; Hörtensteiner, S.

Plant Physiol.

115

677-682

699585

19374909

Crystal structure of red chlorophyll catabolite reductase: enlargement of the ferredoxin-dependent bilin reductase family

2009

Sugishima, M.; Kitamori, Y.; Noguchi, M.; Kohchi, T.; Fukuyama, K.

J. Mol. Biol.

389

376-387

700695

18721307

The control of chlorophyll catabolism and the status of yellowing as a biomarker of leaf senescence

2008

Ougham, H.; Hoertensteiner, S.; Armstead, I.; Donnison, I.; King, I.; Thomas, H.; Mur, L.

Plant Biol.

10 Suppl 1

4-14

712769

20727901

Crystal structures of the substrate-bound forms of red chlorophyll catabolite reductase: implications for site-specific and stereospecific reaction

2010

Sugishima, M.; Okamoto, Y.; Noguchi, M.; Kohchi, T.; Tamiaki, H.; Fukuyama, K.

J. Mol. Biol.

402

879-891

735438

-

Chlorophyll degradation during senescence

2006

Hoertensteiner, S.

Annu. Plant Biol.

57

55-77

735913

11212360

Chlorophyll breakdown in higher plants and algae

1999

Hoertensteiner, S.

Cell. Mol. Life Sci.

56

330-347

736215

-

Breakdown of chlorophyll: A fluorescent chlorophyll catabolite from sweet pepper (Capsicum annuum)

2000

Muehlecker, W.; Kraeutler, B.; Moser, D.; Matile, P.; Hoertensteiner, S.

Helv. Chim. Acta

83

278-286

736949

16228452

Chlorophyll breakdown in oilseed rape

2000

Hoertensteiner, S.; Kraeutler, B.

Photosynth. Res.

64

137-146

736960

15184007

Analysis of the chlorophyll catabolism pathway in leaves of an introgression senescence mutant of Lolium temulentum

2004

Roca, M.; James, C.; Pruzinska, A.; Hoertensteiner, S.; Thomas, H.; Ougham, H.

Phytochemistry

65

1231-1238

Links to other databases for red chlorophyll catabolite

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Show Links (1 entry)