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Ligand (+)-neomenthol Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
C1 0 H2 0 O
(+)-neomenthol
NOOLISFMXDJSKH-UTLUCORTSA-N
(1S,2S,5R)-2-isopropyl-5-methylcyclohexanol, (3S)-neomenthol, D-neomenthol
Related pathways
MetaCyc
menthol biosynthesis
Show all BRENDA pathways known for (+)-neomenthol
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (2 results)
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(-)-menthone + NADPH + H+ = (+)-neomenthol + NADP+
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(-)-menthone + NADPH + H+ = (3S)-neomenthol + NADP+
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-
Substrate in Enzyme-catalyzed Reactions (3 results)
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(+)-neomenthol + NADP+ = (-)-menthone + NADPH + H+
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acetyl-CoA + (+)-neomenthol = CoA + neomenthyl acetate
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UDPglucose + D-neomenthol = UDP + D-neomenthyl-beta-D-glucoside
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Product in Enzyme-catalyzed Reactions (4 results)
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(-)-menthone + NADPH + H+ = (+)-neomenthol + NADP+
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(2R,5R)-isomenthone + NADPH + H+ = (+)-neomenthol + NADP+
-
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(2S,5R)-menthone + NADPH + H+ = (+)-neomenthol + NADP+
-
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(-)-menthone + NADPH + H+ = (3S)-neomenthol + NADP+
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-
Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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KM Value (3 results)
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References & Links Literature References (5)
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Metabolism of monoterpenes: Conversion of l-menthone tol-menthole and d-neomenthol by stereospecific dehydrogenases from peppermint (Mentha piperita) leaves
1982
Kjonaas, R.; Martinkus-Taylor, C.; Croteau, R.
Plant Physiol.
69
1013-1017
Demonstration of the intercellular compartmentation of l-menthone metabolism in peppermint (Mentha piperita) leaves
1982
Croteau, R.; Winters, J.N.
Plant Physiol.
69
975-977
Metabolism of monoterpenes. Evidence for compartmentation of L-menthone metabolism in peppermint (Mentha piperita) leaves
1981
Martinkus, C.; Croteau, R.
Plant Physiol.
68
99-106
Metabolism of monoterpenes. Acetylation of (-)-menthol by a soluble enzyme preparation from peppermint (Mentha piperita) leaves
1978
Croteau, R.; Hooper, C.L.
Plant Physiol.
61
737-742
Molecular cloning and characterization of a broad substrate terpenoid oxidoreductase from Artemisia annua
2010
Ryden, A.; Ruyter-Spira, C.; Litjens, R.; Takahashi, S.; Quax, W.; Osada, H.; Bouwmeester, H.; Kayser, O.
Plant Cell Physiol.
51
1219-1228
Links to other databases for (+)-neomenthol