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The expected taxonomic range for this enzyme is: Allium tuberosum
Reaction Schemes
the enzyme degrades the Aalpha-chain of human fibrinogen but not the Bbeta-chain
Synonyms
AFTEII, alpha-Fibrinogenase,
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the enzyme degrades the Aalpha-chain of human fibrinogen but not the Bbeta-chain
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Human fibrinogen + H2O
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cleavage of the Aalpha-chain, but not of the Bbeta-chain or the gamma-chain by AFTEII
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MeO-Suc-Arg-Pro-Tyr-4-nitroanilide + H2O
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i.e. S-2586, ATFEII is highly specific for the chromogenic chymotrypsin substrate
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leupeptin
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complete inhibition of AFTEII at 1 mM
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brenda
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45000
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x * 45000, AFTEII, SDS-PAGE
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x * 45000, AFTEII, SDS-PAGE
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medicine
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AFTEII may be useful as thrombolytic agent
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Chung, D.M.; Choi, N.S.; Chun, H.K.; Maeng, P.J.; Park, S.B.; Kim, S.H.
A new fibrinolytic enzyme (55 kDa) from Allium tuberosum: purification, characterization, and comparison
J. Med. Food
13
1532-1536
2010
Allium tuberosum
brenda
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